Jack F M Wetzels Selected Research

Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal)

1/2022	Kidney tubule iron loading in experimental focal segmental glomerulosclerosis.
10/2021	Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.
1/2021	Novel in vitro assays to detect circulating permeability factor(s) in idiopathic focal segmental glomerulosclerosis.
1/2015	Differential Expression of Specific Dermatan Sulfate Domains in Renal Pathology.
3/2014	The soluble urokinase receptor is not a clinical marker for focal segmental glomerulosclerosis.
7/2013	New TRPC6 gain-of-function mutation in a non-consanguineous Dutch family with late-onset focal segmental glomerulosclerosis.
4/2013	Vitamin D down-regulates TRPC6 expression in podocyte injury and proteinuric glomerular disease.
2/2013	A retrospective study of focal segmental glomerulosclerosis: clinical criteria can identify patients at high risk for recurrent disease after first renal transplantation.
10/2011	Immunosuppressive treatment of focal segmental glomerulosclerosis: lessons from a randomized controlled trial.
10/2011	Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.

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Jack F M Wetzels Research Topics

Disease

33	Proteinuria 01/2022 - 12/2003
25	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2022 - 05/2004
17	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2022 - 07/2002
16	Chronic Renal Insufficiency 01/2022 - 08/2008
16	Renal Insufficiency (Renal Failure) 01/2020 - 11/2002
14	Chronic Kidney Failure (Chronic Renal Failure) 01/2019 - 06/2003
13	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2022 - 06/2002
11	Albuminuria 01/2020 - 12/2001
10	Atypical Hemolytic Uremic Syndrome 03/2022 - 02/2015
6	Disease Progression 01/2022 - 05/2007
6	Kidney Diseases (Kidney Disease) 01/2022 - 11/2010
5	Fibrosis (Cirrhosis) 01/2022 - 08/2007
5	Nephrogenic Diabetes Insipidus 01/2018 - 07/2009
4	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 10/2021 - 05/2007
4	Acute Kidney Injury (Acute Renal Failure) 01/2020 - 11/2009
4	Thrombotic Microangiopathies 11/2019 - 12/2017
4	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2017 - 04/2012
4	Hyperparathyroidism 02/2016 - 06/2002
4	Anemia 03/2013 - 10/2010
3	Sclerosis 01/2022 - 01/2014
3	Infections 10/2021 - 09/2014
3	Lupus Nephritis 10/2021 - 06/2003
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 04/2012
3	Inflammation (Inflammations) 01/2020 - 01/2012
3	Cysts 01/2017 - 10/2013
3	Breast Neoplasms (Breast Cancer) 10/2015 - 01/2010
3	Polycystic liver disease 05/2015 - 04/2012
3	Diabetic Nephropathies (Diabetic Nephropathy) 01/2015 - 11/2010
3	Neoplasms (Cancer) 06/2014 - 03/2006
3	Atherosclerosis 12/2013 - 11/2004
2	IGA Glomerulonephritis (IGA Nephropathy) 10/2021 - 01/2020
2	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 01/2021 - 01/2020
2	Atrophy 01/2020 - 01/2015
2	Segmental glomerulosclerosis 01/2020 - 11/2006
2	Hypertension (High Blood Pressure) 12/2017 - 11/2015
2	Polyuria 01/2017 - 07/2009
2	Gout 02/2016 - 07/2010
2	Chronic Disease (Chronic Diseases) 01/2015 - 10/2010
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2015 - 06/2003
2	Hyponatremia 12/2013 - 04/2011
2	Heart Failure 06/2012 - 01/2010
2	Diabetes Mellitus 11/2010 - 08/2009

Drug/Important Bio-Agent (IBA)

22	CreatinineIBA 01/2022 - 11/2002
15	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2003
12	eculizumab FDA Link 03/2022 - 02/2015
9	AntibodiesIBA 01/2018 - 12/2001
9	SteroidsIBA 09/2017 - 05/2004
8	HepcidinsIBA 01/2020 - 08/2008
7	IronIBA 01/2022 - 11/2004
7	Biomarkers (Surrogate Marker)IBA 01/2019 - 10/2010
7	Cyclophosphamide (Cytoxan)FDA LinkGeneric 09/2017 - 05/2004
7	Serum AlbuminIBA 02/2013 - 11/2002
6	Complement System Proteins (Complement)IBA 01/2020 - 12/2001
6	TRPC6 Cation ChannelIBA 01/2018 - 10/2011
6	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 01/2017 - 03/2006
6	Vitamin D FDA LinkGeneric 04/2016 - 06/2002
5	Monoclonal AntibodiesIBA 01/2022 - 12/2001
4	Vasopressins (Vasopressin)IBA 01/2018 - 04/2011
4	Rituximab (Mabthera)FDA Link 09/2017 - 07/2007
4	LithiumIBA 01/2017 - 07/2009
4	lanreotide (Somatuline)FDA Link 01/2017 - 04/2012
4	EnzymesIBA 02/2016 - 12/2001
4	Angiotensin IIIBA 06/2014 - 12/2001
4	Immunoglobulin G (IgG)IBA 11/2011 - 12/2005
4	Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)IBA 01/2003 - 12/2001
3	Pharmaceutical PreparationsIBA 03/2022 - 04/2012
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 06/2002
3	AlbuminsIBA 01/2019 - 12/2012
3	Phospholipase A2 ReceptorsIBA 01/2019 - 03/2013
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/2016 - 09/2012
3	Fibroblast Growth Factor-23IBA 04/2016 - 04/2012
3	Prednisone (Sone)FDA LinkGeneric 10/2007 - 04/2003
2	PotassiumIBA 01/2021 - 01/2010
2	NPHS2 proteinIBA 01/2019 - 01/2003
2	Biological ProductsIBA 01/2019 - 10/2012
2	CalcineurinIBA 01/2018 - 10/2011
2	Uremic ToxinsIBA 07/2017 - 04/2011
2	Parathyroid Hormone (Parathormone)IBA 04/2016 - 08/2012
2	Hepatocyte Nuclear FactorsIBA 02/2016 - 10/2013
2	Connective Tissue Growth FactorIBA 01/2015 - 09/2013
2	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 06/2014 - 11/2006
2	LDL CholesterolIBA 02/2014 - 09/2012
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 02/2014 - 09/2012
2	Antihypertensive Agents (Antihypertensives)IBA 02/2014 - 11/2004
2	Aquaporin 2IBA 12/2013 - 04/2011
2	Alkylating AgentsIBA 08/2013 - 06/2010
2	Doxorubicin (Adriamycin)FDA LinkGeneric 04/2013 - 10/2011
2	Contrast MediaIBA 06/2012 - 08/2007
2	Ferritins (Ferritin)IBA 10/2010 - 11/2004
2	Urea (Carbamide)FDA LinkGeneric 07/2010 - 11/2002
2	Peptide Receptors (Peptide Receptor)IBA 07/2010 - 03/2006
2	Octreotide (Sandostatin)FDA LinkGeneric 07/2010 - 03/2006
2	GelatinIBA 03/2006 - 03/2006
2	Somatostatin Receptors (Somatostatin Receptor)IBA 03/2006 - 03/2006
2	Peptides (Polypeptides)IBA 03/2006 - 03/2006

Therapy/Procedure

19	Therapeutics 01/2022 - 06/2002
12	Kidney Transplantation 01/2021 - 01/2003
5	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2019 - 06/2003
2	Transplantation 09/2013 - 06/2003
2	Plasma Exchange 04/2008 - 03/2004